A Day in the Lab

A Day in the Lab: Improvising with 3D-Printing for Standardised Experiments

Join me in the lab as we innovate with 3D-printing technology to design custom equipment that aids in the standardisation of cell migration assays in our experiments.

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A Day in the Lab: Harnessing a Nobel-Winning Technique

Join me in the lab as we use the groundbreaking technique of phase-contrast microscopy, a Nobel-prize winning method, to study living cells in depth and gain insights into cellular structure and proliferation.

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A Day in the Lab: Microscopic Exploration of Muscle Biopsies

Join me today in the lab as we explore muscle biopsies under the microscope. After immunostaining them, we mount these samples on slides for in-depth scrutiny, specifically examining the intricacies of neuromuscular junctions.

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A Day in the Lab

A Day in the Lab: Deciphering pH Levels with Colour

Join me in the lab today as we delve into a colourful world of pH indicators, using phenol red to gauge pH levels in our experiment involving cultured brain cells. Let's explore the colour spectrum of pH!

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A Day in the Lab

A Day in the Lab: Preparing Proteins for Long-Term Storage

Join me in the lab today as I prepare a stock of a protein for long-term storage, ensuring its integrity and functionality for future research.

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A Day in the Lab

A Day in the Lab: Rapidly Amplifying Genes with Bacteria

Join me in today's lab session where I am exploiting the power of bacteria to swiftly duplicate a human gene. Genetic amplification has never been this fascinating!

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A Day in the Lab

A Day in the Lab: Employing Viruses to Transfer Genes into Cells

Join me in today's lab session where I leverage a virus to transport a specific gene into a mammalian cell. A fascinating mix of genetics and virology!

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A Day in the Lab: Safely Handling Liquid Nitrogen

Let's delve into the laboratory today where I will share my experience with liquid nitrogen and how to handle it safely for long-term preservation of brain tissue.

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A Day in the Lab: Speeding up Pipetting

Join me in the lab today as I share tips on how to speed up biochemical assays using a multichannel micropipette, and common pipetting errors to avoid.

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A Day in the Lab

A Day in the Lab: Dissecting a Brain

Join me in the lab today as I delve into a brain dissection, preserving cells in a special medium for future growth and experimentation.

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A Day in the Lab

A Day in the Lab: Determining Protein Concentrations with a Biochemical Assay

Dive into the world of biochemical assays with me, as I work on determining the concentration of a protein released by brain cells.

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A Day in the Lab

A Day in the Lab: Determining Genotypes with PCR and Gel Electrophoresis

Join me in the lab as I perform genotyping to determine genetic mutations in specific genes from the latest litters of our lab's colonies.

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A Day in the Lab

A Day in the Lab: Visualising DNA through Gel Electrophoresis

Join me as I conduct genotyping in the lab, utilising gel electrophoresis to identify DNA samples harboring a specific mutation.

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A Day in the Lab: Removing the Meninges from the Brain

Dive into the meticulous procedure of brain dissection, focusing on the careful removal of the meninges, a crucial step for effective glial cell culture.

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A Day in the Lab: Cryopreservation of Brain Cells

Explore the intricate process of cryopreserving brain cells in the lab, ensuring their viability for future experimentation.

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A Day in the Lab

A Day in the Lab: Extracting Plasmid DNA from Bacterial Cultures

This blog post unveils the fascinating procedure of a miniprep experiment, aiming to purify plasmid DNA from bacterial cultures.

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A Day in the Lab

A Day in the Lab: Delving into Neonatal Brain Dissection for Glial Cells

In this blog post, I delve into the intricate process of dissecting neonatal brains to extract glial cells, followed by culturing them for further scientific experiments.

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A Day in the Lab

A Day in the Lab: Investigating Isolated Microglia from Neonatal Brains

This blog post offers an inside look at the investigation of brain microglia, dissected from neonatal brains and cultured in a lab, scrutinising their morphology and culture purity using a phase-contrast microscope.

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A Day in the Lab

A Day in the Lab: The Art and Science of Phase-contrast microscopy

This blog post takes you on a journey into the lab, showcasing how phase-contrast microscopy is employed to inspect the health and confluency of cultured cells, a critical factor before they are utilised in scientific experiments.

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A Day in the Lab

A Day in the Lab: Bacterial transformation

This blog post presents a snapshot of a day in the lab spent conducting a bacterial transformation experiment, resulting in genetically modified bacteria cloning and expressing a specific gene of interest.

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A Day in the Lab

A Day in the Lab: Inoculating bacterial cultures

A day in the lab, dedicated to inoculating bacterial cultures to enable self-cloning and DNA replication. Discover the process, from broth preparation to sterile conditions.

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A Day in The Lab: Investigating Calcium Activity in the White Matter

Take a peek into a day at the lab, focused on exploring the calcium activity of the white matter within the corpus callosum, utilising 2-photon microscopy, intricate coding, and innovative methodologies.

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A Day in the Lab

A Day in the Lab: Analysing the Electrical Activity of Neurons using Computer Code

The blog post delves into the analytical side of neuroscience, exploring the process of examining neuronal electrical activity using Matlab software and a host of complex mathematical functions, complete with data visualisations.

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A Day in the Lab

A Day in the Lab: Unravelling Neuronal Activity using Electrophysiology

Join me on a fascinating journey in the lab as I employ the sophisticated patch-clamp technique in an electrophysiology experiment to record neuronal activity.

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A Day in the Lab

A Day in the Lab: Decoding the Histopathological Alterations in Brain Slices Post-Stroke

Join me as I delve into a day in the lab, analysing H&E stained brain slices to unravel the histopathological transformations following a stroke.

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A Day in the Lab

A Day in the Lab: Hematoxylin & Eosin Staining for Microscopical Analysis of the Brain

In this detailed account of a recent neuroscience experiment, I guide you through the meticulous process of staining brain slices using Hematoxylin & Eosin (H&E), shedding light on the intricate steps involved in studying the effects of a novel therapeutic approach to stroke treatment.

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A Day in the Lab

A Day in the Lab: Delving into the World of Image Analysis for Stroke Research

An engaging behind-the-scenes look at the meticulous process of analysing MRI scans to explore potential stroke treatments, offering a unique perspective on the complex world of medical research.

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